STL5-T-0057
Modify Date: 2024-04-03 18:44:59
STL5-T-0057 structure
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Common Name | STL5-T-0057 | ||
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| CAS Number | 2756014-24-9 | Molecular Weight | 445.94 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H24ClN3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of STL5-T-0057STL5-T-0057 (compound 68) is an selective ALDH1 B1 inhibitor with an IC50 value of 30 nM. STL5-T-0057 inhibits cell growth of SW480 cells in adherent and spheroid conditions with IC50 values of 2.46 and 0.39 μM, respectively. STL5-T-0057 can be used for the research of cancer[1]. |
| Name | STL5-T-0057 |
|---|
| Description | STL5-T-0057 (compound 68) is an selective ALDH1 B1 inhibitor with an IC50 value of 30 nM. STL5-T-0057 inhibits cell growth of SW480 cells in adherent and spheroid conditions with IC50 values of 2.46 and 0.39 μM, respectively. STL5-T-0057 can be used for the research of cancer[1]. |
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| Related Catalog | |
| Target |
IC50: 30 nM (ALDH1 B1), 2.46 μM (SW480, adherent), 0.39 μM (SW480, spheroid)[1] |
| In Vitro | STL5-T-0057 (0-10 μM) inhibits ALDH1 B1 with an IC50 value of 30 nM[1]. STL5-T-0057 (0.01-10 μM; 4-5 d) inhibits cell growth of HEK293T cells[1]. STL5-T-0057 (0.01-10 μM) inhibits cell viability of SW480 cells in adherent and spheroid conditions with IC50 values of 2.46 and 0.39 μM, respectively[1]. Cell Cytotoxicity Assay[1] Cell Line: HEK293T cell line Concentration: 0.01-10 μM Incubation Time: 4-5 d Result: Showed cell cytotoxicity to HEK293T cells with a GI50 value of 1.7 μM. |
| References |
| Molecular Formula | C26H24ClN3O2 |
|---|---|
| Molecular Weight | 445.94 |