CDK9-IN-29

Modify Date: 2024-07-16 15:06:42

CDK9-IN-29 Structure
CDK9-IN-29 structure
Common Name CDK9-IN-29
CAS Number 2737262-24-5 Molecular Weight 553.60
Density N/A Boiling Point N/A
Molecular Formula C29H33F2N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CDK9-IN-29


CDK9-IN-29 (compound Z11) is a potent CDK9 inhibitor (IC50 = 3.20 nM) with good kinase selectivity. CDK9-IN-29 inhibits cell proliferation and induces apoptosis[1].

 Names

Name CDK9-IN-29

 CDK9-IN-29 Biological Activity

Description CDK9-IN-29 (compound Z11) is a potent CDK9 inhibitor (IC50 = 3.20 nM) with good kinase selectivity. CDK9-IN-29 inhibits cell proliferation and induces apoptosis[1].
Related Catalog
References

[1]. Tizhi Wu, et al. Discovery of Selective and Potent Macrocyclic CDK9 Inhibitors for the Treatment of Osimertinib-Resistant Non-Small-Cell Lung Cancer. J Med Chem. 2023.  

 Chemical & Physical Properties

Molecular Formula C29H33F2N5O4
Molecular Weight 553.60