DS45500853

Modify Date: 2024-01-14 12:22:27

DS45500853 Structure
DS45500853 structure
Common Name DS45500853
CAS Number 2735803-28-6 Molecular Weight 284.35
Density N/A Boiling Point N/A
Molecular Formula C18H20O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DS45500853


DS45500853 is an estrogen-related receptor α (ERRα) agonist. DS45500853 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD; 1.2 μM) with an >IC50 value of 0.80 μM. DS45500853 can be used for the research of metabolic disorders, including type 2 diabetes mellitus (T2DM)[1].

 Names

Name DS45500853

 DS45500853 Biological Activity

Description DS45500853 is an estrogen-related receptor α (ERRα) agonist. DS45500853 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD; 1.2 μM) with an >IC50 value of 0.80 μM. DS45500853 can be used for the research of metabolic disorders, including type 2 diabetes mellitus (T2DM)[1].
Related Catalog
Target

ERRα

References

[1]. Shinozuka T, et al. Discovery of a Novel Class of ERRα Agonists. ACS Med Chem Lett. 2021 Apr 21;12(5):817-821.

 Chemical & Physical Properties

Molecular Formula C18H20O3
Molecular Weight 284.35
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