Norflurazon

Modify Date: 2024-01-08 04:24:24

Norflurazon structure	Common Name	Norflurazon
	CAS Number	27314-13-2	Molecular Weight	303.67
	Density	1.5±0.1 g/cm3	Boiling Point	345.2±52.0 °C at 760 mmHg
	Molecular Formula	C₁₂H₉ClF₃N₃O	Melting Point	184ºC
	MSDS	Chinese USA	Flash Point	162.6±30.7 °C
	Symbol	GHS09	Signal Word	Warning

Use of Norflurazon

Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity[1].

Name	norflurazon
Synonym	More Synonyms

Description	Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Abrous-Belbachir O, et, al. Evidence that norflurazon affects chloroplast lipid unsaturation in soybean leaves (Glycine max L.). J Agric Food Chem. 2009 Dec 9;57(23):11434-40.

Density	1.5±0.1 g/cm3
Boiling Point	345.2±52.0 °C at 760 mmHg
Melting Point	184ºC
Molecular Formula	C₁₂H₉ClF₃N₃O
Molecular Weight	303.67
Flash Point	162.6±30.7 °C
Exact Mass	303.038635
PSA	46.92000
LogP	2.45
Appearance of Characters	Crystalline Solid \| White
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.567

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UR6150000

CHEMICAL NAME :: 3(2H)-Pyridazinone, 4-chloro-5-(methylamino)-2-(alpha,alpha,alpha-trifluo ro-m-tolyl)-

CAS REGISTRY NUMBER :: 27314-13-2

BEILSTEIN REFERENCE NO. :: 0757115

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C12-H9-Cl-F3-N3-O

MOLECULAR WEIGHT :: 303.69

WISWESSER LINE NOTATION :: T6NNVJ BR CXFFF& DG EM1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85ARAE "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revision Volume(issue)/page/year: 2,108,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >20 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,624,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: >1250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C221,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: >1250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C221,1991 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Symbol	GHS09
Signal Word	Warning
Hazard Statements	H400
Precautionary Statements	P273
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	N: Dangerous for the environment;
Risk Phrases	R50
Safety Phrases	61
RIDADR	UN 3077 9/PG 3
RTECS	UR6150000

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Norflurazon

CAS#:27314-13-2

Literature: Konecny, Vaclav; Kovac, Stefan; Varkonda, Stefan Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 2 p. 492 - 502

A new F131V mutation in Chlamydomonas phytoene desaturase locates a cluster of norflurazon resistance mutations near the FAD-binding site in 3D protein models.

PLoS ONE 9(6) , e99894, (2014)

The green alga Chlamydomonas reinhardtii provides a tractable genetic model to study herbicide mode of action using forward genetics. The herbicide norflurazon inhibits phytoene desaturase, which is r...

Novel bioassay for the discovery of inhibitors of the 2-C-methyl-D-erythritol 4-phosphate (MEP) and terpenoid pathways leading to carotenoid biosynthesis.

PLoS ONE 9(7) , e103704, (2014)

The 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway leads to the synthesis of isopentenyl diphosphate in plastids. It is a major branch point providing precursors for the synthesis of carotenoids, t...

Functional characterization of the two ferrochelatases in Arabidopsis thaliana.

Plant Cell Environ. 38(2) , 280-98, (2015)

The enzyme ferrochelatase catalyses the formation of protoheme by inserting Fe(2+) into protoporphyrin IX. Although most organisms express only one ferrochelatase, all land plants analysed so far poss...

4-Chlor-5-(methylamino)-2-[3-(trifluormethyl)phenyl]pyridazin-3(2H)-on

4-Chloro-5-(methylamino)-2-[3-(trifluoromethyl)phenyl]pyridazin-3(2H)-one

4-Chloro-5-(methylamino)-2-(a,a,a-trifluoro-m-tolyl)-3(2H)-pyridazinone

4-Chloro-5-(methylamino)-2-(α,α,α-trifluoro-m-tolyl)-3(2H)-pyridazinone

EINECS 248-397-1

MFCD00128055

3(2H)-Pyridazinone, 4-chloro-5-(methylamino)-2-[3-(trifluoromethyl)phenyl]-

4-chloro-5-methylamino-2-(α,α,α-trifluoro-m-tolyl)pyridazin-3(2H)-one

4-Chloro-5-(methylamino)-2-[3-(trifluoromethyl)phenyl]-3(2H)-pyridazinone

4-Chloro-5-(methylamino)-2-(3-(trifluoromethyl)phenyl)-3(2H)-pyridazinone (9CI)

4-chloro-5-(methylamino)-2-[3-(trifluoromethyl)phenyl]pyridazin-3-one

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Norflurazon
Price: ￥1688.0/100mg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Norflurazon
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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