ALK/EGFR-IN-3

Modify Date: 2024-01-16 21:29:40

ALK/EGFR-IN-3 structure	Common Name	ALK/EGFR-IN-3
	CAS Number	2730432-72-9	Molecular Weight	572.12
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₃₄ClN₇O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ALK/EGFR-IN-3

ALK/EGFR-IN-3 is a dual inhibitor of ALK and EGFR. ALK/EGFR-IN-3 inhibits the cell proliferation of H1975, PC9, and Baf3-EML4-ALK cancer cell lines with IC50s of 0.1360, 0.0332, and 0.0339 μM, respectively[1].

Name	ALK/EGFR-IN-3

Description	ALK/EGFR-IN-3 is a dual inhibitor of ALK and EGFR. ALK/EGFR-IN-3 inhibits the cell proliferation of H1975, PC9, and Baf3-EML4-ALK cancer cell lines with IC50s of 0.1360, 0.0332, and 0.0339 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK
References	[1]. An B, et al. Discovery of potent and effective inhibitors containing sulfoxide structures targeting EML4-ALK rearrangement and EGFR mutant non-small cell lung cancer. Bioorg Chem. 2023 Sep;138:106653.

Molecular Formula	C₂₇H₃₄ClN₇O₃S
Molecular Weight	572.12

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