ALK/EGFR-IN-3

Names

[ CAS No. ]:
2730432-72-9

[ Name ]:
ALK/EGFR-IN-3

Biological Activity

[Description]:

ALK/EGFR-IN-3 is a dual inhibitor of ALK and EGFR. ALK/EGFR-IN-3 inhibits the cell proliferation of H1975, PC9, and Baf3-EML4-ALK cancer cell lines with IC50s of 0.1360, 0.0332, and 0.0339 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK

[References]

[1]. An B, et al. Discovery of potent and effective inhibitors containing sulfoxide structures targeting EML4-ALK rearrangement and EGFR mutant non-small cell lung cancer. Bioorg Chem. 2023 Sep;138:106653.  

Chemical & Physical Properties

[ Molecular Formula ]:
C27H34ClN7O3S

[ Molecular Weight ]:
572.12

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.