G2019S-LRRK2 inhibitor 38

Modify Date: 2024-01-20 16:42:42

G2019S-LRRK2 inhibitor 38 structure	Common Name	G2019S-LRRK2 inhibitor 38
	CAS Number	2704564-03-2	Molecular Weight	379.467
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₁N₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of G2019S-LRRK2 inhibitor 38

G2019S-LRRK2 inhibitor 38 is a potent, selective, brain penetrant G2019S-LRRK2 kinase inhibitor with IC50 of <1 nM, cellular EC50 of 40 nM, >2,000-fold selectivity over WT LRRK2 (cellular EC50>100 uM).G2019S-LRRK2 inhibitor 38 selectively inhibit phosphorylation of Ser935 in vitro, and in brain, lung, kidney and spleen in G2019S-LRRK2 mice.

Name	G2019S-LRRK2 inhibitor 38

Description	G2019S-LRRK2 inhibitor 38 is a potent, selective, brain penetrant G2019S-LRRK2 kinase inhibitor with IC50 of <1 nM, cellular EC50 of 40 nM, >2,000-fold selectivity over WT LRRK2 (cellular EC50>100 uM).G2019S-LRRK2 inhibitor 38 selectively inhibit phosphorylation of Ser935 in vitro, and in brain, lung, kidney and spleen in G2019S-LRRK2 mice.
References	1. Robert K Leśniak, et al. Eur J Med Chem. 2022 Feb 5;229:114080.

Molecular Formula	C₂₄H₂₁N₅
Molecular Weight	379.467

DC Chemicals Limited
China
Product Name: G2019S-LRRK2 inhibitor 38
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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