Coronalolic acid
Modify Date: 2025-08-31 19:03:24
Coronalolic acid structure
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Common Name | Coronalolic acid | ||
|---|---|---|---|---|
| CAS Number | 268214-52-4 | Molecular Weight | 470.684 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 608.7±25.0 °C at 760 mmHg | |
| Molecular Formula | C30H46O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 335.9±19.7 °C | |
Use of Coronalolic acidCoronalolic acid, extract from the apical bud of Gardenia sootepenesis Hutch, inhibits TNF-α-induced NF-κB activity and NO production[1]. |
| Name | 3-[(1R,3aS,3bS,6R,6aR,7aS,9aR)-6-(3-Hydroxy-1-propen-2-yl)-3a,9a- dimethyl-1-[(2R,5E)-6-methyl-7-oxo-5-hepten-2-yl]decahydro-1H-cyc lopenta[a]cyclopropa[e]naphthalen-6a(7H)-yl]propanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Coronalolic acid, extract from the apical bud of Gardenia sootepenesis Hutch, inhibits TNF-α-induced NF-κB activity and NO production[1]. |
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| Related Catalog | |
| Target |
NF-κB |
| In Vitro | Coronalolic acid has an inhibition effect against the TNF-α-induced NF-κB activity and NO production with IC50s of 15.4 μM and 15.0 μM in LPS-stimulated RAW 264.7 cells, respectively[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 608.7±25.0 °C at 760 mmHg |
| Molecular Formula | C30H46O4 |
| Molecular Weight | 470.684 |
| Flash Point | 335.9±19.7 °C |
| Exact Mass | 470.339600 |
| PSA | 74.60000 |
| LogP | 7.24 |
| Vapour Pressure | 0.0±4.0 mmHg at 25°C |
| Index of Refraction | 1.551 |
| InChIKey | IOFXIXOKOAYADV-ICQJXUMVSA-N |
| SMILES | C=C(CO)C1CCC2C3(C)CCC(C(C)CCC=C(C)C=O)C3(C)CCC23CC13CCC(=O)O |
| Hazard Codes | Xi |
|---|
| Coronalolic acid |
| 1H-Cyclopenta[a]cyclopropa[e]naphthalene-6a(7H)-propanoic acid, 1-[(1R,4E)-1,5-dimethyl-6-oxo-4-hexen-1-yl]decahydro-6-[1-(hydroxymethyl)ethenyl]-3a,9a-dimethyl-, (1R,3aS,3bS,6R,6aR,7aS,9aR)- |
| 3-[(1R,3aS,3bS,6R,6aR,7aS,9aR)-6-(3-Hydroxy-1-propen-2-yl)-3a,9a-dimethyl-1-[(2R,5E)-6-methyl-7-oxo-5-hepten-2-yl]decahydro-1H-cyclopenta[a]cyclopropa[e]naphthalen-6a(7H)-yl]propanoic acid |