BET BD2-IN-1
Modify Date: 2024-04-09 11:59:26
BET BD2-IN-1 structure
|
Common Name | BET BD2-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 2677039-24-4 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BET BD2-IN-1BET BD2-IN-1 (compound 45) is a potent and selective inhibitor of BET BD2 (IC50=1.6 nM). BET BD2-IN-1 inhibits the differentiation of Th17 cells by decreasing the activation of STAT3 and NF-κB. BET BD2-IN-1 is used in psoriasis and inflammatory bowel disease (IBD) research[1]. |
| Name | BET BD2-IN-1 |
|---|
| Description | BET BD2-IN-1 (compound 45) is a potent and selective inhibitor of BET BD2 (IC50=1.6 nM). BET BD2-IN-1 inhibits the differentiation of Th17 cells by decreasing the activation of STAT3 and NF-κB. BET BD2-IN-1 is used in psoriasis and inflammatory bowel disease (IBD) research[1]. |
|---|---|
| Related Catalog | |
| Target |
BRD2 BD1:570 nM (IC50) BRD2 BD2:5.9 nM (IC50) BRD3 BD1:465 nM (IC50) BRD3 BD2:6.0 mM (IC50) BRD4 BD1:524 nM (IC50) BRD4 BD2:1.6 nM (IC50) BRDT BD1:527 nM (IC50) |
| InChIKey | GVCFSBGCJBRHFS-UHFFFAOYSA-N |
|---|---|
| SMILES | CN1CCC(NC(=O)c2cccc(CN3c4ccccc4C=C4c5c(cccc53)C(=O)N4C)c2)CC1 |