BET BD2-IN-1

Modify Date: 2024-04-09 11:59:26

BET BD2-IN-1 Structure
BET BD2-IN-1 structure
Common Name BET BD2-IN-1
CAS Number 2677039-24-4 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BET BD2-IN-1


BET BD2-IN-1 (compound 45) is a potent and selective inhibitor of BET BD2 (IC50=1.6 nM). BET BD2-IN-1 inhibits the differentiation of Th17 cells by decreasing the activation of STAT3 and NF-κB. BET BD2-IN-1 is used in psoriasis and inflammatory bowel disease (IBD) research[1].

 Names

Name BET BD2-IN-1

 BET BD2-IN-1 Biological Activity

Description BET BD2-IN-1 (compound 45) is a potent and selective inhibitor of BET BD2 (IC50=1.6 nM). BET BD2-IN-1 inhibits the differentiation of Th17 cells by decreasing the activation of STAT3 and NF-κB. BET BD2-IN-1 is used in psoriasis and inflammatory bowel disease (IBD) research[1].
Related Catalog
Target

BRD2 BD1:570 nM (IC50)

BRD2 BD2:5.9 nM (IC50)

BRD3 BD1:465 nM (IC50)

BRD3 BD2:6.0 mM (IC50)

BRD4 BD1:524 nM (IC50)

BRD4 BD2:1.6 nM (IC50)

BRDT BD1:527 nM (IC50)

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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