2677039-24-4
2677039-24-4 structure
- Name: BET BD2-IN-1
- Chemical Name: BET BD2-IN-1
- CAS Number: 2677039-24-4
- Molecular Formula:
- Molecular Weight:
- Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
- Create Date: 2024-04-09 11:59:26
- Modify Date: 2024-04-09 11:59:26
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BET BD2-IN-1 (compound 45) is a potent and selective inhibitor of BET BD2 (IC50=1.6 nM). BET BD2-IN-1 inhibits the differentiation of Th17 cells by decreasing the activation of STAT3 and NF-κB. BET BD2-IN-1 is used in psoriasis and inflammatory bowel disease (IBD) research[1].
| Name | BET BD2-IN-1 |
|---|
| Description | BET BD2-IN-1 (compound 45) is a potent and selective inhibitor of BET BD2 (IC50=1.6 nM). BET BD2-IN-1 inhibits the differentiation of Th17 cells by decreasing the activation of STAT3 and NF-κB. BET BD2-IN-1 is used in psoriasis and inflammatory bowel disease (IBD) research[1]. |
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| Related Catalog | |
| Target |
BRD2 BD1:570 nM (IC50) BRD2 BD2:5.9 nM (IC50) BRD3 BD1:465 nM (IC50) BRD3 BD2:6.0 mM (IC50) BRD4 BD1:524 nM (IC50) BRD4 BD2:1.6 nM (IC50) BRDT BD1:527 nM (IC50) |
| No Any Chemical & Physical Properties |