D-erythro-Sphingosine hydrochloride structure
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Common Name | D-erythro-Sphingosine hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 2673-72-5 | Molecular Weight | 335.95300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H38ClNO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of D-erythro-Sphingosine hydrochlorideD-erythro-Sphingosine (Erythrosphingosine) hydrochloride is a specific TRPM3 activator. D-erythro-Sphingosine also induces retinoblastoma protein dephosphorylation[1][2]. |
| Name | D-erythro-Sphingosine hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | D-erythro-Sphingosine (Erythrosphingosine) hydrochloride is a specific TRPM3 activator. D-erythro-Sphingosine also induces retinoblastoma protein dephosphorylation[1][2]. |
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| Related Catalog | |
| Target |
TRPM3 Retinoblastoma protein |
| In Vitro | Extracellular application of D-erythro-Sphingosine (20 μM) induces an increase in [Ca2+]i in TRPM3-transfected HEK293 cells within 20 to 30 s after start of application, whereas nontransfected control cells (NT) shows only very small responses[1]. D-erythro-Sphingosine (10 μM) induces currents through TRPM3[1]. Induction of retinoblastoma protein dephosphorylation by D-erythro-Sphingosine (500 nM; 24 h) precede inhibition of growth and a specific arrest in the G0/G1 phase of the cell cycle[2]. |
| Molecular Formula | C18H38ClNO2 |
|---|---|
| Molecular Weight | 335.95300 |
| Exact Mass | 335.25900 |
| PSA | 66.48000 |
| LogP | 5.42650 |
| InChIKey | YDIHJJLAPMAISR-ZNWYJMOFSA-N |
| SMILES | CCCCCCCCCCCCCC=CC(O)C(N)CO.Cl |
| d-sphingosine hcl |