FGFR-IN-11
Modify Date: 2024-01-12 19:16:20
FGFR-IN-11 structure
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Common Name | FGFR-IN-11 | ||
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| CAS Number | 2658488-68-5 | Molecular Weight | 521.01 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H29ClN4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FGFR-IN-11FGFR-IN-11 (compound I-5) is an orally active and covalent FGFR inhibitor with IC50 values of 9.9 nM (FGFR1), 3.1 nM (FGFR2), 16 nM (FGFR3), and 1.8 nM (FGFR4), respectively. FGFR-IN-11 inhibits multiple cancer cell proliferation with nanomolar activity. FGFR-IN-11 inhibits tumor growth significantly in xenograft mice models[1]. |
| Name | FGFR-IN-11 |
|---|
| Description | FGFR-IN-11 (compound I-5) is an orally active and covalent FGFR inhibitor with IC50 values of 9.9 nM (FGFR1), 3.1 nM (FGFR2), 16 nM (FGFR3), and 1.8 nM (FGFR4), respectively. FGFR-IN-11 inhibits multiple cancer cell proliferation with nanomolar activity. FGFR-IN-11 inhibits tumor growth significantly in xenograft mice models[1]. |
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| Related Catalog | |
| Target |
FGFR1:9.9 nM (IC50) FGFR2:3.1 nM (IC50) FGFR3:16 nM (IC50) FGFR4:1.8 nM (IC50) |
| References |
| Molecular Formula | C28H29ClN4O4 |
|---|---|
| Molecular Weight | 521.01 |