JDQ-443

Modify Date: 2024-01-02 01:20:46

JDQ-443 Structure
JDQ-443 structure
Common Name JDQ-443
CAS Number 2653994-08-0 Molecular Weight 526.03
Density N/A Boiling Point N/A
Molecular Formula C29H28ClN7O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JDQ-443


JDQ-443 (example 1a) is a covalent KRAS G12C inhibitor (extracted from patent WO2021120890A1)[1].

 Names

Name JDQ-443

 JDQ-443 Biological Activity

Description JDQ-443 (example 1a) is a covalent KRAS G12C inhibitor (extracted from patent WO2021120890A1)[1].
Related Catalog
Target

KRas G12C

In Vitro JDQ-443 (NVP-JDQ443) traps the GDP-bound inactive conformation of KRAS[1].
References

[1]. LIU BO, et al. PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS. Patent WO2021120890A1.

 Chemical & Physical Properties

Molecular Formula C29H28ClN7O
Molecular Weight 526.03
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