2653994-08-0
2653994-08-0 structure
- Name: JDQ-443
- Chemical Name: JDQ-443
- CAS Number: 2653994-08-0
- Molecular Formula: C29H28ClN7O
- Molecular Weight: 526.03
- Catalog: Signaling Pathways GPCR/G Protein Ras
- Create Date: 2022-01-03 16:54:24
- Modify Date: 2024-01-02 01:20:46
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JDQ-443 (example 1a) is a covalent KRAS G12C inhibitor (extracted from patent WO2021120890A1)[1].
| Name | JDQ-443 |
|---|
| Description | JDQ-443 (example 1a) is a covalent KRAS G12C inhibitor (extracted from patent WO2021120890A1)[1]. |
|---|---|
| Related Catalog | |
| Target |
KRas G12C |
| In Vitro | JDQ-443 (NVP-JDQ443) traps the GDP-bound inactive conformation of KRAS[1]. |
| References |
[1]. LIU BO, et al. PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS. Patent WO2021120890A1. |
| Molecular Formula | C29H28ClN7O |
|---|---|
| Molecular Weight | 526.03 |