DGKα-IN-2

DGKα-IN-2 Structure
DGKα-IN-2 structure
Common Name DGKα-IN-2
CAS Number 2648556-92-5 Molecular Weight 461.43
Density N/A Boiling Point N/A
Molecular Formula C23H22F3N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DGKα-IN-2


DGKα-IN-2 (example 48) is a DGKα inhibitor with the IC50 of 0.9 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study.

 Names

Name DGKα-IN-2

 DGKα-IN-2 Biological Activity

Description DGKα-IN-2 (example 48) is a DGKα inhibitor with the IC50 of 0.9 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study.
Related Catalog
Target

0.9 nM (DGKα)

References

[1]. Schmees, Norbert, et al. Preparation of substituted aminoquinolones as DGKα inhibitors for immune activation. WO2021105115.

 Chemical & Physical Properties

Molecular Formula C23H22F3N3O4
Molecular Weight 461.43
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