2648556-92-5

2648556-92-5 structure

Name: DGKα-IN-2
Chemical Name: DGKα-IN-2
CAS Number: 2648556-92-5
Molecular Formula: C₂₃H₂₂F₃N₃O₄
Molecular Weight: 461.43
Catalog: Research Areas Cancer
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DGKα-IN-2 (example 48) is a DGKα inhibitor with the IC50 of 0.9 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study.

Name	DGKα-IN-2

Description	DGKα-IN-2 (example 48) is a DGKα inhibitor with the IC50 of 0.9 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study.
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology
Target	0.9 nM (DGKα)
References	[1]. Schmees, Norbert, et al. Preparation of substituted aminoquinolones as DGKα inhibitors for immune activation. WO2021105115.

Molecular Formula	C₂₃H₂₂F₃N₃O₄
Molecular Weight	461.43