HIF-2α-IN-9

Modify Date: 2024-01-11 21:27:05

HIF-2α-IN-9 structure	Common Name	HIF-2α-IN-9
	CAS Number	2648334-36-3	Molecular Weight	380.35
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₃F₅O₄S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of HIF-2α-IN-9

HIF-2α-IN-9 (compound 35r) is an inhibitor ofHIF-2α. HIF-2α-IN-9 inhibits VEGF-A (IC50=305 nM), and regulates growth-promoting genes in tumor cells, reactivates macrophage-mediated tumor immunity[1].

Name	HIF-2α-IN-9

Description	HIF-2α-IN-9 (compound 35r) is an inhibitor ofHIF-2α. HIF-2α-IN-9 inhibits VEGF-A (IC50=305 nM), and regulates growth-promoting genes in tumor cells, reactivates macrophage-mediated tumor immunity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase
Target	HIF-2α[1]
References	[1]. Buchstaller H P, et al. Discovery of Cycloalkyl [c] thiophenes as Novel Scaffolds for Hypoxia-Inducible Factor-2伪 Inhibitors[J]. Journal of Medicinal Chemistry, 2023..

Molecular Formula	C₁₂H₁₃F₅O₄S₂
Molecular Weight	380.35

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