Thalidomide-NH-PEG7

Modify Date: 2024-01-11 11:58:33

Thalidomide-NH-PEG7 structure	Common Name	Thalidomide-NH-PEG7
	CAS Number	2641838-98-2	Molecular Weight	581.61
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₃₉N₃O₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Thalidomide-NH-PEG7

Thalidomide-NH-PEG7 is a synthesized E3 ligase ligand-linker conjugate for ADC. Thalidomide-NH-PEG7 can be connected to the ligand for protein by a linker to form PROTAC iRucaparib-AP6, a highly specific PARP1 degrader[1].

Name	Thalidomide-NH-PEG7

Description	Thalidomide-NH-PEG7 is a synthesized E3 ligase ligand-linker conjugate for ADC. Thalidomide-NH-PEG7 can be connected to the ligand for protein by a linker to form PROTAC iRucaparib-AP6, a highly specific PARP1 degrader[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	Cereblon
References	[1]. Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation.Nat Chem Biol. 2019 Dec;15(12):1223-1231.

Molecular Formula	C₂₇H₃₉N₃O₁₁
Molecular Weight	581.61

Hazard Codes	Xi

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Thalidomide-NH-PEG7
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Thalidomide-NH-PEG7

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.