SMD-3040 intermediate-2

Modify Date: 2025-09-02 06:44:37

SMD-3040 intermediate-2 structure	Common Name	SMD-3040 intermediate-2
	CAS Number	2632308-00-8	Molecular Weight	389.92
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₈ClN₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SMD-3040 intermediate-2

SMD-3040 intermediate-2 is an intermediate in the synthesis of SMD-3040 (HY-156568). SMD-3040 contains SMARCA2/4 ligands, linker and VHL ligands and is a selective SMARCA2 degrader. MD-3040 can be used for ADC drug synthesis and has strong tumor growth inhibition in tumor xenograft models[1].

Name	SMD-3040 intermediate-2

Description	SMD-3040 intermediate-2 is an intermediate in the synthesis of SMD-3040 (HY-156568). SMD-3040 contains SMARCA2/4 ligands, linker and VHL ligands and is a selective SMARCA2 degrader. MD-3040 can be used for ADC drug synthesis and has strong tumor growth inhibition in tumor xenograft models[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Yang L, et.al. Discovery of SMD-3040 as a Potent and Selective SMARCA2 PROTAC Degrader with Strong in vivo Antitumor Activity. J Med Chem. 2023 Jul 31.

Molecular Formula	C₂₁H₂₈ClN₃O₂
Molecular Weight	389.92
InChIKey	WXLUHNJCOLNWIB-UHFFFAOYSA-N
SMILES	CC1CC2(CCN(C(=O)OC(C)(C)C)CC2)CN1c1ccc(C#N)c(Cl)c1

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SMD-3040 intermediate-2

Use of SMD-3040 intermediate-2

Names

SMD-3040 intermediate-2 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.