2632308-00-8

2632308-00-8 structure

Name: SMD-3040 intermediate-2
Chemical Name: SMD-3040 intermediate-2
CAS Number: 2632308-00-8
Molecular Formula: C₂₁H₂₈ClN₃O₂
Molecular Weight: 389.92
Catalog: Research Areas Cancer
Create Date: 2024-03-14 18:20:36
Modify Date: 2025-09-02 06:44:37
SMD-3040 intermediate-2 is an intermediate in the synthesis of SMD-3040 (HY-156568). SMD-3040 contains SMARCA2/4 ligands, linker and VHL ligands and is a selective SMARCA2 degrader. MD-3040 can be used for ADC drug synthesis and has strong tumor growth inhibition in tumor xenograft models[1].

Name	SMD-3040 intermediate-2

Description	SMD-3040 intermediate-2 is an intermediate in the synthesis of SMD-3040 (HY-156568). SMD-3040 contains SMARCA2/4 ligands, linker and VHL ligands and is a selective SMARCA2 degrader. MD-3040 can be used for ADC drug synthesis and has strong tumor growth inhibition in tumor xenograft models[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Yang L, et.al. Discovery of SMD-3040 as a Potent and Selective SMARCA2 PROTAC Degrader with Strong in vivo Antitumor Activity. J Med Chem. 2023 Jul 31.

Molecular Formula	C₂₁H₂₈ClN₃O₂
Molecular Weight	389.92