(Rac)-Etavopivat
Modify Date: 2024-02-21 09:46:48
(Rac)-Etavopivat structure
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Common Name | (Rac)-Etavopivat | ||
|---|---|---|---|---|
| CAS Number | 2622070-93-1 | Molecular Weight | 457.50 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H23N3O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (Rac)-Etavopivat(Rac)-Etavopivat ((Rac)-FT-4202) is an isomer of Etavopivat (HY-139573). Etavopivat is an orally active erythrocyte pyruvate kinase-R (PKR) activator that can be used in studies of sickle cell disease and other haemoglobinopathies[1]. |
| Name | (Rac)-Etavopivat |
|---|
| Description | (Rac)-Etavopivat ((Rac)-FT-4202) is an isomer of Etavopivat (HY-139573). Etavopivat is an orally active erythrocyte pyruvate kinase-R (PKR) activator that can be used in studies of sickle cell disease and other haemoglobinopathies[1]. |
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| Related Catalog | |
| In Vitro | Etavopivat (20 μM, 4 h)可以改善人红细胞中血红蛋白-氧亲和力并降低了镰状点 (PoS)[1]。 |
| In Vivo | Etavopivat（口服，3-22mg/kg，每天一次，5天）在 8 mg/kg和 22 mg/kg 的剂量下引起食蟹猴 2,3-DPG 和 ATP 的增加[1]。 |
| References |
| Molecular Formula | C22H23N3O6S |
|---|---|
| Molecular Weight | 457.50 |