5-Chloro-2-methyl-4-isothiazolin-3-one

Modify Date: 2024-01-02 16:32:54

5-Chloro-2-methyl-4-isothiazolin-3-one Structure
5-Chloro-2-methyl-4-isothiazolin-3-one structure
Common Name 5-Chloro-2-methyl-4-isothiazolin-3-one
CAS Number 26172-55-4 Molecular Weight 149.599
Density 1.5±0.1 g/cm3 Boiling Point 200.2±50.0 °C at 760 mmHg
Molecular Formula C4H4ClNOS Melting Point 42-45?C
MSDS N/A Flash Point 74.9±30.1 °C

 Names

Name chloromethylisothiazolinone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 200.2±50.0 °C at 760 mmHg
Melting Point 42-45?C
Molecular Formula C4H4ClNOS
Molecular Weight 149.599
Flash Point 74.9±30.1 °C
Exact Mass 148.970215
PSA 50.24000
LogP 0.24
Vapour Pressure 0.3±0.4 mmHg at 25°C
Index of Refraction 1.628
Stability Stable. Incompatible with strong oxidizing agents.

 MSDS

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 5-Chloro-2-methyl-4-isothiazolin-3-one, tech grade, ¿14% in water. CMI/MI ¿2.0
Synonyms:CMI

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:5-Chloro-2-methyl-4-isothiazolin-3-one, tech grade, ¿14% in water. CMI/MI ¿2.0
CAS number:26172-55-4

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels, refrigerated.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C4H4ClNOS
Molecular weight:149.6

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride, sulfur oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NX8156850
CHEMICAL NAME :
4-Isothiazolin-3-one, 5-chloro-2-methyl-
CAS REGISTRY NUMBER :
26172-55-4
LAST UPDATED :
199710
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C4-H4-Cl-N-O-S
MOLECULAR WEIGHT :
149.60
WISWESSER LINE NOTATION :
T5SNVJ B1 EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
200 ng/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 118,129,1983 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3204 No. of Facilities: 2332 (estimated) No. of Industries: 24 No. of Occupations: 25 No. of Employees: 42106 (estimated) No. of Female Employees: 17003 (estimated)

 Safety Information

Hazard Codes C:Corrosive
Risk Phrases R20/21/22;R34;R43;R50
Safety Phrases S26-S36/37/39-S45-S60-S61-S24-S28
RIDADR UN 1760 8/PG 2
WGK Germany 1
RTECS NX8156850
Packaging Group III
Hazard Class 8
HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

chloromethylisothiazolinone
5-chloro-2-methylisothiazol-3(2h)-one
EINECS 247-500-7
5-Chloro-2-methyl-4-isothiazolin-3-one
5-Chloro-2-methyl-1,2-thiazol-3(2H)-one
Methylchloroisothiazolinone
MFCD00792550
3(2H)-Isothiazolone, 5-chloro-2-methyl-
5-Chloro-2-methyl-3-isothiazolone
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