3-(3-hydroxypropyl)-8-[(E)-2-(3-methoxyphenyl)ethenyl]-7-methyl-1-prop-2-ynylpurine-2,6-dione
![3-(3-hydroxypropyl)-8-[(E)-2-(3-methoxyphenyl)ethenyl]-7-methyl-1-prop-2-ynylpurine-2,6-dione Structure](https://image.chemsrc.com/caspic/415/261717-18-4.png)
3-(3-hydroxypropyl)-8-[(E)-2-(3-methoxyphenyl)ethenyl]-7-methyl-1-prop-2-ynylpurine-2,6-dione structure
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Common Name | 3-(3-hydroxypropyl)-8-[(E)-2-(3-methoxyphenyl)ethenyl]-7-methyl-1-prop-2-ynylpurine-2,6-dione | ||
|---|---|---|---|---|
| CAS Number | 261717-18-4 | Molecular Weight | 394.42400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H22N4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 3-(3-hydroxypropyl)-8-[(E)-2-(3-methoxyphenyl)ethenyl]-7-methyl-1-prop-2-ynylpurine-2,6-dioneMSX-2 is A2A adenosine receptor antagonist, with Ki of 5 nM in human that plays an important role in Parkinson's disease[1][2]. |
| Name | 3-(3-hydroxypropyl)-8-[(E)-2-(3-methoxyphenyl)ethenyl]-7-methyl-1-prop-2-ynylpurine-2,6-dione |
|---|---|
| Synonym | More Synonyms |
| Description | MSX-2 is A2A adenosine receptor antagonist, with Ki of 5 nM in human that plays an important role in Parkinson's disease[1][2]. |
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| Related Catalog | |
| References |
| Molecular Formula | C21H22N4O4 |
|---|---|
| Molecular Weight | 394.42400 |
| Exact Mass | 394.16400 |
| PSA | 91.28000 |
| LogP | 1.09130 |
| InChIKey | FWLDDFYHEQMIGG-MDZDMXLPSA-N |
| SMILES | C#CCn1c(=O)c2c(nc(C=Cc3cccc(OC)c3)n2C)n(CCCO)c1=O |
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~92%
3-(3-hydroxypro... CAS#:261717-18-4 |
| Literature: Hockemeyer, Joerg; Burbiel, Joachim C.; Mueller, Christa E. Journal of Organic Chemistry, 2004 , vol. 69, # 10 p. 3308 - 3318 |
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~%
3-(3-hydroxypro... CAS#:261717-18-4 |
| Literature: Hockemeyer, Joerg; Burbiel, Joachim C.; Mueller, Christa E. Journal of Organic Chemistry, 2004 , vol. 69, # 10 p. 3308 - 3318 |
|
~%
3-(3-hydroxypro... CAS#:261717-18-4 |
| Literature: Hockemeyer, Joerg; Burbiel, Joachim C.; Mueller, Christa E. Journal of Organic Chemistry, 2004 , vol. 69, # 10 p. 3308 - 3318 |
|
~%
3-(3-hydroxypro... CAS#:261717-18-4 |
| Literature: Hockemeyer, Joerg; Burbiel, Joachim C.; Mueller, Christa E. Journal of Organic Chemistry, 2004 , vol. 69, # 10 p. 3308 - 3318 |
|
~%
3-(3-hydroxypro... CAS#:261717-18-4 |
| Literature: Sauer, Roland; Maurinsh, Juris; Reith, Ulrike; Fuelle, Friederike; Klotz, Karl-Norbert; Mueller, Christa E. Journal of Medicinal Chemistry, 2000 , vol. 43, # 3 p. 440 - 448 |
|
~%
3-(3-hydroxypro... CAS#:261717-18-4 |
| Literature: Hockemeyer, Joerg; Burbiel, Joachim C.; Mueller, Christa E. Journal of Organic Chemistry, 2004 , vol. 69, # 10 p. 3308 - 3318 |
|
~93%
3-(3-hydroxypro... CAS#:261717-18-4 |
| Literature: Sauer, Roland; Maurinsh, Juris; Reith, Ulrike; Fuelle, Friederike; Klotz, Karl-Norbert; Mueller, Christa E. Journal of Medicinal Chemistry, 2000 , vol. 43, # 3 p. 440 - 448 |
![(E)-3-[8-[2-(3-methoxyphenyl)vinyl]-7-methyl-2,6-dioxo-1-prop-2-ynyl-1,2,6,7-tetrahydropurin-3-yl]propyl acetate structure](https://image.chemsrc.com/caspic/173/702697-16-3.png)
![(E)-N-[6-amino-1-(3-hydroxypropyl)-2,4-dioxo-3-prop-2-ynyl-1,2,3,4-tetrahydropyrimidin-5-yl]-3-(3-methoxyphenyl)acrylamide structure](https://image.chemsrc.com/caspic/087/261705-85-5.png)
| (E)-3-(3-hydroxypropyl)-8-[2-(3-methoxyphenyl)vinyl]-7-methyl-1-prop-2-ynyl-3,7-dihydropurine-2,6-dione |
| MSX-2 |
| 3-(3-hdyroxypropyl)-7-methyl-8-(m-methoxystyryl)-1-propargylxanthine |
| 3-(3-Hydroxypropyl)-8-(m-methoxystyryl)-7-methyl-1-propargylxanthine |