Tinlorafenib structure
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Common Name | Tinlorafenib | ||
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CAS Number | 2573781-75-4 | Molecular Weight | 456.89 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C19H19ClF2N4O3S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of TinlorafenibTinlorafenib (PF-07284890) (compound 10) is an orally active BRAF kinase inhibitor, with IC50s of 4.25 and 2.7 nM for BRAFV600E/V600K respectively. Tinlorafenib demonstrates CNS penetration and can be used in the research of BRAF-associated malignant and benign tumors of the CNS as well as extracranial malignancies[1]. |
Name | Tinlorafenib |
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Description | Tinlorafenib (PF-07284890) (compound 10) is an orally active BRAF kinase inhibitor, with IC50s of 4.25 and 2.7 nM for BRAFV600E/V600K respectively. Tinlorafenib demonstrates CNS penetration and can be used in the research of BRAF-associated malignant and benign tumors of the CNS as well as extracranial malignancies[1]. |
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Related Catalog | |
Target |
BRafV600E:4.25 nM (IC50) BRafV600K:2.7 nM (IC50) |
References |
Molecular Formula | C19H19ClF2N4O3S |
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Molecular Weight | 456.89 |