3-Glycidoxypropyltrimethoxysilane

Modify Date: 2025-08-21 11:13:02

3-Glycidoxypropyltrimethoxysilane Structure
3-Glycidoxypropyltrimethoxysilane structure
 Common Name 3-Glycidoxypropyltrimethoxysilane
CAS Number 2530-83-8 Molecular Weight 236.338
Density 1.0±0.1 g/cm3 Boiling Point 299.4±0.0 °C at 760 mmHg
Molecular Formula C9H20O5Si Melting Point -50°C
MSDS Chinese USA Flash Point 81.9±22.2 °C
Symbol GHS05
GHS05		 Signal Word Danger

 Names

Name 3-Glycidoxypropyltrimethoxysilane
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 299.4±0.0 °C at 760 mmHg
Melting Point -50°C
Molecular Formula C9H20O5Si
Molecular Weight 236.338
Flash Point 81.9±22.2 °C
Exact Mass 236.108002
PSA 49.45000
LogP 0.28
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.436
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VV4025000
CHEMICAL NAME :
Silane, 3-(2,3-epoxypropoxy)propyltrimethoxy-
CAS REGISTRY NUMBER :
2530-83-8
LAST UPDATED :
199710
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C9-H20-O5-Si
MOLECULAR WEIGHT :
236.38
WISWESSER LINE NOTATION :
T3OTJ B1O3-SI-O1&O1&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
22600 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5300 mg/m3/4H
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
3970 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
119 mg/m3/6H/4W-I
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ug/plate
REFERENCE :
TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS215156 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0269 No. of Facilities: 142 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 247 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0269 No. of Facilities: 4854 (estimated) No. of Industries: 40 No. of Occupations: 60 No. of Employees: 68889 (estimated) No. of Female Employees: 12321 (estimated)

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H318
Precautionary Statements P280-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes Xn:Harmful;
Risk Phrases R21;R36/38
Safety Phrases S28A-S26
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS VV4025000
Packaging Group III
HS Code 29310095

 Synthetic Route

Allyl glycidyl ether structure

Allyl glycidyl ether

CAS#:106-92-3

Trimethoxysilane structure

Trimethoxysilane

CAS#:2487-90-3

~80%

3-Glycidoxypropyltrimethoxysilane Structure

3-Glycidoxyprop...

CAS#:2530-83-8

Literature: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY; YOO, Bok Ryul; HAN, Joon Soo; YOO, Jang Hyun Patent: WO2011/81277 A2, 2011 ; Location in patent: Page/Page column 21 ;

 Customs

HS Code 29310095

 Articles34

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 Synonyms

Glycidoxypropyl Trimethoxy Silane
Silane, trimethoxy[3-(oxiranylmethoxy)propyl]-
Z 6040
[3-(Glycidyloxy)propyl]trimethoxysilane
UNII:5K9X9X899R
Silane, [3-(2,3-epoxypropoxy)propyl]trimethoxy-
3-GlycidyloxypropyltriMethoxysilane
Y 4087
DZ 6040
KBM 430
silquest A187 silane
Silane, trimethoxy[3- (oxiranylmethoxy)propyl]-
γ-Glycidoxypropyltrimethoxysilane
[γ-(Glycidyloxy)propyl]trimethoxysilane
Trimethoxy[3-(oxiran-2-ylmethoxy)propyl]silane
Pivadorm
(γ-Glycidoxypropyl)trimethoxysilane
gamma-Glycidoxypropyltrimethoxysilane
Trimethoxy(3-(oxiran-2-ylmethoxy)propyl)silane
EINECS 219-784-2
NUCA 187
MFCD00005144
KBM 403
A 187
CG6720
3-Glycidoxypropyltrimethoxysilane
Trimethoxy[3-(2-oxiranylmethoxy)propyl]silane
[[3-(Trimethoxysilyl)propoxy]methyl]oxirane
GLYMO
Glycidyl 3-Trimethoxysilylpropyl Ether
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