PBIT
Modify Date: 2025-08-25 13:18:52
PBIT structure
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Common Name | PBIT | ||
|---|---|---|---|---|
| CAS Number | 2514-30-9 | Molecular Weight | 241.31 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 418.2±38.0 °C at 760 mmHg | |
| Molecular Formula | C14H11NOS | Melting Point | N/A | |
| MSDS | USA | Flash Point | 206.7±26.8 °C | |
Use of PBITPBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1(JARID1) enzymes. PBIT inhibits JARID1B (KDM5B or PLU1 ) histone demethylase an IC50 of about 3 μM . PBIT also inhibits JARID1A and JARID1C with IC5 s of 6 and 4.9 μM, respectively[1]. |
| Name | 2-(4-methylphenyl)-1,2-benzothiazol-3-one |
|---|---|
| Synonym | More Synonyms |
| Description | PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1(JARID1) enzymes. PBIT inhibits JARID1B (KDM5B or PLU1 ) histone demethylase an IC50 of about 3 μM . PBIT also inhibits JARID1A and JARID1C with IC5 s of 6 and 4.9 μM, respectively[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 418.2±38.0 °C at 760 mmHg |
| Molecular Formula | C14H11NOS |
| Molecular Weight | 241.31 |
| Flash Point | 206.7±26.8 °C |
| Exact Mass | 241.056137 |
| PSA | 50.24000 |
| LogP | 3.73 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.680 |
| RIDADR | NONH for all modes of transport |
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CAS#:1442-03-1| 2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one |
| 2-(p-tolyl)benzo[d]isothiazol-3(2H)-one |
| 2-p-Tolyl-benz[d]isothiazol-3-on |
| 2-(4-Methylphenyl)-1,2-benzothiazol-3(2H)-one |
| 2-p-tolyl-benz[d]isothiazol-3-one |
| 2-(4-Methylphenyl)-2,3-dihydrobenzisothiazol-3-one 2-p-Tolyl-1,2-benzisothiazolin-3-one |
| 2-(p-methylphenyl)-1,2-benzisothiazolin-3-one |
| 2-(4-methylphenyl)benzo[d]isothiazol-3(2H)-one |
| 2-p-tolyl-benzo[d]isothiazol-3-one |
| HMS1493C06 |
| 1,2-Benzisothiazol-3(2H)-one, 2-(4-methylphenyl)- |
| HMS2576N21 |
| PBIT |