(R)-(-)-NIPECOTIC ACID ETHYL ESTER structure 
             | 
        Common Name | (R)-(-)-NIPECOTIC ACID ETHYL ESTER | ||
|---|---|---|---|---|
| CAS Number | 25137-01-3 | Molecular Weight | 157.210 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 238.6±0.0 °C at 760 mmHg | |
| Molecular Formula | C8H15NO2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 90.6±0.0 °C | |
| Symbol | 
             
            
             
            
            GHS05, GHS07  | 
        Signal Word | Danger | |
| Name | Ethyl (3R)-piperidine-3-carboxylate | 
|---|---|
| Synonym | More Synonyms | 
| Density | 1.0±0.1 g/cm3 | 
|---|---|
| Boiling Point | 238.6±0.0 °C at 760 mmHg | 
| Molecular Formula | C8H15NO2 | 
| Molecular Weight | 157.210 | 
| Flash Point | 90.6±0.0 °C | 
| Exact Mass | 157.110275 | 
| PSA | 38.33000 | 
| LogP | 0.96 | 
| Vapour Pressure | 0.0±0.4 mmHg at 25°C | 
| Index of Refraction | 1.449 | 
| Storage condition | Refrigerator | 
| Symbol | 
                                    
                                     
                                    
                                     
                                    
                                    GHS05, GHS07  | 
                            
|---|---|
| Signal Word | Danger | 
| Hazard Statements | H315-H318-H335 | 
| Precautionary Statements | P261-P280-P305 + P351 + P338 | 
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter | 
| Hazard Codes | Xi | 
| Risk Phrases | 36/37/38-41-37/38 | 
| Safety Phrases | S26-S36/37/39-S39-S36 | 
| RIDADR | NONH for all modes of transport | 
| HS Code | 2933399090 | 
| 
                                        
                                        
                                        
                                        
                                        
                                        
                                         ~20%  
                                            (R)-(-)-NIPECOT... CAS#:25137-01-3  | 
                                
| Literature: Yamanaka, Toshio; Ohkubo, Mitsuru; Takahashi, Fumie; Kato, Masayuki Tetrahedron Letters, 2004 , vol. 45, # 13 p. 2843 - 2845 | 
| 
                                        
                                        
                                        
                                        
                                        
                                        
                                         ~%  
                                            (R)-(-)-NIPECOT... CAS#:25137-01-3  | 
                                
| Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 70, p. 899,913 Chemische Berichte, , vol. 102, p. 2864 Gazzetta Chimica Italiana, , vol. 102, p. 189,190, 192, 193 | 
| 
                                        
                                        
                                        
                                        
                                        
                                        
                                         ~%  
                                            (R)-(-)-NIPECOT... CAS#:25137-01-3  | 
                                
| Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 70, p. 899,913 | 
| Precursor 2 | |
|---|---|
| DownStream 8 | |
| HS Code | 2933399090 | 
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% | 
| 
                                    
                                    THIP analgesia: cross tolerance with morphine.
                                    
                                    
                                     Life Sci. 32(19) , 2265-72, (1983) THIP (4,5,6,7-tetrahydroisoxazolo (5,4-c) pyridone-3-ol), a direct acting GABA receptor agonist, has been shown to have antinociceptive properties. To determine whether tolerance develops to the analg...  | 
                                |
| 
                                    
                                    (R)-nipecotic acid ethyl ester: a direct-acting cholinergic agonist that displays greater efficacy at M2 than at M1 muscarinic receptors.
                                    
                                    
                                     J. Pharmacol. Exp. Ther. 242(1) , 173-8, (1987) Previous reports have suggested that the ethyl ester of (R)-nipecotic acid ethyl ester [(R)-NAEE] displays cholinomimetic properties in vivo. The present study was undertaken to characterize more full...  | 
                                |
| 
                                    
                                    Differential effects of ethyl (R,S)-nipecotate on the behaviors of highly and minimally aggressive female golden hamsters.
                                    
                                    
                                     Psychopharmacology 89(4) , 444-8, (1986) The GABA uptake inhibitor ethyl (R,S)-nipecotate produces a dose-dependent suppression of aggression in highly aggressive hamsters but not in minimally aggressive ones. This suppression occurs at dose...  | 
                                
| (R)-Ethyl nipecotate | 
| Ethyl (R)-3-Piperidinecarboxylate | 
| (R)-Ethylpiperidine-3-carboxylate | 
| Ethyl (R)-nipecotate | 
| (R)-(-)-Nipecotic Acid Ethyl Ester | 
| (R)-(-)-Ethyl nipecotate | 
| (R)-Nipecotic acid ethyl ester | 
| ethyl R-nipecotate | 
| Ethyl (R)-(-)-piperidine-3-carboxylate | 
| (R)-(-)-3-Piperidinecarboxylic Acid Ethyl Ester | 
| 3-Piperidinecarboxylic acid, ethyl ester, (3R)- | 
| Ethyl (R)-(-)-3-Piperidinecarboxylate | 
| Ethyl (R)-(-)-Nipecotate | 
| MFCD03093637 | 
| Ethyl (3R)-3-piperidinecarboxylate | 
| Ethyl (3R)-piperidine-3-carboxylate | 
| (R)-Ethyl piperidine-3-carboxylate | 
| D-Nipecotic acid ethyl ester |