Dihydro-5-azacytidine acetate

Modify Date: 2024-01-11 19:29:08

Dihydro-5-azacytidine acetate structure	Common Name	Dihydro-5-azacytidine acetate
	CAS Number	2470972-18-8	Molecular Weight	306.27
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₈N₄O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Dihydro-5-azacytidine acetate

Dihydro-5-azacytidine acetate (DHAC), the nucleoside analog, is incorporated into DNA and inhibits DNA methylation. Dihydro-5-azacytidine acetate has an antitumor activity[1][2].

Name	Dihydro-5-azacytidine acetate

Description	Dihydro-5-azacytidine acetate (DHAC), the nucleoside analog, is incorporated into DNA and inhibits DNA methylation. Dihydro-5-azacytidine acetate has an antitumor activity[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Signaling Pathways >> Epigenetics >> DNA Methyltransferase
References	[1]. Robert A Kratzke, et al. Response to the methylation inhibitor dihydro-5-azacytidine in mesothelioma is not associated with methylation of p16INK4a: results of cancer and leukemia group B 159904. J Thorac Oncol. 2008 Apr;3(4):417-21. [2]. W C Powell, et al. Biochemical pharmacology of 5,6-dihydro-5-azacytidine (DHAC) and DNA hypomethylation in tumor (L1210)-bearing mice. Cancer Chemother Pharmacol. 1988;21(2):117-21.

Description

Dihydro-5-azacytidine acetate (DHAC), the nucleoside analog, is incorporated into DNA and inhibits DNA methylation. Dihydro-5-azacytidine acetate has an antitumor activity[1][2].

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Signaling Pathways >> Epigenetics >> DNA Methyltransferase

References

[1]. Robert A Kratzke, et al. Response to the methylation inhibitor dihydro-5-azacytidine in mesothelioma is not associated with methylation of p16INK4a: results of cancer and leukemia group B 159904. J Thorac Oncol. 2008 Apr;3(4):417-21.

[2]. W C Powell, et al. Biochemical pharmacology of 5,6-dihydro-5-azacytidine (DHAC) and DNA hypomethylation in tumor (L1210)-bearing mice. Cancer Chemother Pharmacol. 1988;21(2):117-21.

Molecular Formula	C₁₀H₁₈N₄O₇
Molecular Weight	306.27

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Dihydro-5-azacytidine acetate

Use of Dihydro-5-azacytidine acetate

Names

Dihydro-5-azacytidine acetate Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.