Apoptosis inducer 8

Modify Date: 2024-04-03 13:04:57

Apoptosis inducer 8 structure	Common Name	Apoptosis inducer 8
	CAS Number	2470024-51-0	Molecular Weight	507.97
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₂₂ClN₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Apoptosis inducer 8

Apoptosis inducer 8 (Compound 7c) is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading lung cancer burden. Apoptosis inducer 8 significantly reduced the gal-1 protein level. Apoptosis inducer 8 is also a PET imaging agent[1].

Name	Apoptosis inducer 8

Description	Apoptosis inducer 8 (Compound 7c) is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading lung cancer burden. Apoptosis inducer 8 significantly reduced the gal-1 protein level. Apoptosis inducer 8 is also a PET imaging agent[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	Apoptosis inducer 8 (Compound 7c) exhibits an excellent growth inhibition against A-549, NCI-H460, MCF-7 and MDA-MB-23 cells with IC50 values of 0.63 ± 0.21, 0.99 ± 0.01, 1.3 ± 0.18 and 0.94 ± 0.02 µM, respectively[1].
References	[1]. Sridhar Goud N, et al. Novel benzimidazole-triazole hybrids as apoptosis inducing agents in lung cancer: Design, synthesis, 18F-radiolabeling & galectin-1 inhibition studies. Bioorg Chem. 2020 Sep;102:104125.

Molecular Formula	C₂₉H₂₂ClN₅O₂
Molecular Weight	507.97

Apoptosis inducer 8

Use of Apoptosis inducer 8

Names

Apoptosis inducer 8 Biological Activity

Chemical & Physical Properties