Apoptosis inducer 10
Modify Date: 2025-08-27 13:37:12
Apoptosis inducer 10 structure
|
Common Name | Apoptosis inducer 10 | ||
|---|---|---|---|---|
| CAS Number | 2379310-39-9 | Molecular Weight | 430.67 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H46N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Apoptosis inducer 10Apoptosis inducer 10 is a potent apoptosis inducer. Apoptosis inducer 10 shows antiproliferative effect. Apoptosis inducer 10 induces apoptosis in HeLa cancer cells via a mitochondria-dependent endogenous pathway[1]. |
| Name | Apoptosis inducer 10 |
|---|
| Description | Apoptosis inducer 10 is a potent apoptosis inducer. Apoptosis inducer 10 shows antiproliferative effect. Apoptosis inducer 10 induces apoptosis in HeLa cancer cells via a mitochondria-dependent endogenous pathway[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Apoptosis inducer 10 (compound 11) shows cytotoxic activity with IC50s of 7.39, 63.20, 15.28, 15.38, 12.07 µM for HeLa, HL-7702, A549, PC-3, MCF-7 cells, respectively[1]. Apoptosis inducer 10 (2.5, 5, 10 µM) inhibits tumor cell colony formation in A549, HeLa, PC-3 and MCF-7 cells[1]. Apoptosis inducer 10 (2.5, 5, 10 µM; 48 h) induces apoptosis in HeLa cells in a dose dependent manner[1]. Apoptosis inducer 10 (0, 2.5, 5, 10, 20 µM; 72 h) decreases the ratio to the expression of Bcl-2 and Bax in HeLa cells and resultes in the release of cytochrome c, thereby activates caspase-9 and caspase-3, and cleaved PARP proteins[1]. |
| References |
| Molecular Formula | C27H46N2O2 |
|---|---|
| Molecular Weight | 430.67 |