2470024-51-0

2470024-51-0 structure

Name: Apoptosis inducer 8
Chemical Name: Apoptosis inducer 8
CAS Number: 2470024-51-0
Molecular Formula: C₂₉H₂₂ClN₅O₂
Molecular Weight: 507.97
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2022-08-21 00:44:32
Modify Date: 2024-04-03 13:04:57
Apoptosis inducer 8 (Compound 7c) is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading lung cancer burden. Apoptosis inducer 8 significantly reduced the gal-1 protein level. Apoptosis inducer 8 is also a PET imaging agent[1].

Name	Apoptosis inducer 8

Description	Apoptosis inducer 8 (Compound 7c) is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading lung cancer burden. Apoptosis inducer 8 significantly reduced the gal-1 protein level. Apoptosis inducer 8 is also a PET imaging agent[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	Apoptosis inducer 8 (Compound 7c) exhibits an excellent growth inhibition against A-549, NCI-H460, MCF-7 and MDA-MB-23 cells with IC50 values of 0.63 ± 0.21, 0.99 ± 0.01, 1.3 ± 0.18 and 0.94 ± 0.02 µM, respectively[1].
References	[1]. Sridhar Goud N, et al. Novel benzimidazole-triazole hybrids as apoptosis inducing agents in lung cancer: Design, synthesis, 18F-radiolabeling & galectin-1 inhibition studies. Bioorg Chem. 2020 Sep;102:104125.

Molecular Formula	C₂₉H₂₂ClN₅O₂
Molecular Weight	507.97