(Aminooxy)acetamide-Val-Cit-PAB-MMAE
Modify Date: 2025-09-10 18:28:34
(Aminooxy)acetamide-Val-Cit-PAB-MMAE structure
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Common Name | (Aminooxy)acetamide-Val-Cit-PAB-MMAE | ||
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| CAS Number | 2446645-88-9 | Molecular Weight | 1196.48 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C60H97N11O14 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (Aminooxy)acetamide-Val-Cit-PAB-MMAE(Aminooxy)acetamide-Val-Cit-PAB-MMAE (MMAE 5) is an intermediate used in the synthetic preparation of drug-linker conjugates for ADC. (Aminooxy)acetamide-Val-Cit-PAB-MMAE is conjugated to polyamide via oxime bond formation to form MMAE polyamide conjugate. Then MMAE polyamide conjugate can be conjugated to Trastuzumab, to make ADC[1]. |
| Name | (Aminooxy)acetamide-Val-Cit-PAB-MMAE |
|---|
| Description | (Aminooxy)acetamide-Val-Cit-PAB-MMAE (MMAE 5) is an intermediate used in the synthetic preparation of drug-linker conjugates for ADC. (Aminooxy)acetamide-Val-Cit-PAB-MMAE is conjugated to polyamide via oxime bond formation to form MMAE polyamide conjugate. Then MMAE polyamide conjugate can be conjugated to Trastuzumab, to make ADC[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C60H97N11O14 |
|---|---|
| Molecular Weight | 1196.48 |
| InChIKey | FEBOYCQLTPBAFA-BKOKITGHSA-N |
| SMILES | CCC(C)C(C(CC(=O)N1CCCC1C(OC)C(C)C(=O)NC(C)C(O)c1ccccc1)OC)N(C)C(=O)C(NC(=O)C(C(C)C)N(C)C(=O)OCc1ccc(NC(=O)C(CCCNC(N)=O)NC(=O)C(NC(=O)CON)C(C)C)cc1)C(C)C |