(AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE
Modify Date: 2024-01-13 19:01:17
![(AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE Structure](https://www.chemsrc.com/caspic/035/244277-89-2.png)
(AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE structure
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Common Name | (AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE | ||
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| CAS Number | 244277-89-2 | Molecular Weight | 384.55 | |
| Density | N/A | Boiling Point | 744.6ºC at 760 mmHg | |
| Molecular Formula | C24H36N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 404.1ºC | |
Use of (AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATEJ-104129 is a selective and orally active muscarinic M3 receptor antagonist (Ki = 4.2 nM). J-104129 is effective in promoting bronchodilation[1][2]. |
| Name | but-2-enedioic acid,(2R)-2-cyclopentyl-2-hydroxy-N-[1-(4-methylpent-3-enyl)piperidin-4-yl]-2-phenylacetamide |
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| Description | J-104129 is a selective and orally active muscarinic M3 receptor antagonist (Ki = 4.2 nM). J-104129 is effective in promoting bronchodilation[1][2]. |
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| Related Catalog | |
| In Vivo | J-104129 (10 mg/kg; p.o.; single) 在大鼠中表现出持续超过 10 h 的持久支气管扩张作用[1][2]。 J-104129 (p.o.) 在大鼠中拮抗 ACh 诱导的支气管收缩，ED50 值为 0.58 mg/kg[1]。 Animal Model: Male Sprague-Dawley rats[1][2]. Dosage: 10 mg/kg Administration: Oral administration; single. Result: Exhibited bronchodilatory activity. |
| References |
| Boiling Point | 744.6ºC at 760 mmHg |
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| Molecular Formula | C24H36N2O2 |
| Molecular Weight | 384.55 |
| Flash Point | 404.1ºC |
| Exact Mass | 500.28900 |
| PSA | 127.17000 |
| LogP | 4.04190 |
| Vapour Pressure | 2.77E-23mmHg at 25°C |