UIAA-II-232

Modify Date: 2023-02-24 18:27:20

Use of UIAA-II-232

UIAA-II-232 (compound 19b) is a potent DNA gyrase catalytic inhibitor with an IC50 value of 3.5 µM[1].

Name	UIAA-II-232

Description	UIAA-II-232 (compound 19b) is a potent DNA gyrase catalytic inhibitor with an IC50 value of 3.5 µM[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
Target	IC50: 3.5 µM (DNA gyrase catalytic)[1].
References	[1]. Aguirre AL, et al. Identification of an ethyl 5,6-dihydropyrazolo[1,5-c]quinazoline-1-carboxylate as a catalytic inhibitor of DNA gyrase. Bioorg Med Chem. 2020 May 15;28(10):115439.

Molecular Formula	C₂₀H₂₄FN₅O₃
Molecular Weight	401.43