UIAA-II-232

Names

[ CAS No. ]:
2428407-03-6

[ Name ]:
UIAA-II-232

Biological Activity

[Description]:

UIAA-II-232 (compound 19b) is a potent DNA gyrase catalytic inhibitor with an IC50 value of 3.5 µM[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

[Target]

IC50: 3.5 µM (DNA gyrase catalytic)[1].

[References]

[1]. Aguirre AL, et al. Identification of an ethyl 5,6-dihydropyrazolo[1,5-c]quinazoline-1-carboxylate as a catalytic inhibitor of DNA gyrase. Bioorg Med Chem. 2020 May 15;28(10):115439.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₄FN₅O₃

[ Molecular Weight ]:
401.43

Related Compounds

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