UNII:E9μ425FIB

Modify Date: 2024-01-02 16:44:34

UNII:E9μ425FIB structure	Common Name	UNII:E9μ425FIB
	CAS Number	2425-79-8	Molecular Weight	202.247
	Density	1.1±0.1 g/cm3	Boiling Point	266.0±0.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₈O₄	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	122.1±30.0 °C
	Symbol	GHS07	Signal Word	Warning

Name	1,4-Butanediol diglycidyl ether
Synonym	More Synonyms

Density	1.1±0.1 g/cm3
Boiling Point	266.0±0.0 °C at 760 mmHg
Molecular Formula	C₁₀H₁₈O₄
Molecular Weight	202.247
Flash Point	122.1±30.0 °C
Exact Mass	202.120514
PSA	43.52000
LogP	0.27
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.476
Water Solubility	SOLUBLE

UNII:E9μ425FIB MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EJ5100000

CHEMICAL NAME :: Butane, 1,4-bis(2,3-epoxypropoxy)-

CAS REGISTRY NUMBER :: 2425-79-8

BEILSTEIN REFERENCE NO. :: 0115238

LAST UPDATED :: 199712

DATA ITEMS CITED :: 20

MOLECULAR FORMULA :: C10-H18-O4

MOLECULAR WEIGHT :: 202.28

WISWESSER LINE NOTATION :: T3OTJ B1O4O1- BT3OTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1134 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - somnolence (general depressed activity) Skin and Appendages - hair

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >250 ppm/6H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1100 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1130 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8470 mg/kg/11D-C

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 32960 mg/kg/2Y-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - dehydration Skin and Appendages - tumors

TYPE OF TEST :: Specific locus test

TYPE OF TEST :: Heritable translocation test

TYPE OF TEST :: Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 6250 nmol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 249,55,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2226 No. of Facilities: 43 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 606 (estimated) No. of Female Employees: 51 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302 + H312 + H332-H315-H317-H319-H412
Precautionary Statements	P273-P280-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn:Harmful;
Risk Phrases	R20/21;R36/38;R43
Safety Phrases	S26-S28-S37/39-S28B
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	EJ5100000
HS Code	2910900090

1,4-Butanediol

CAS#:110-63-4

Epichlorohydrin

CAS#:106-89-8

~72%

UNII:E9μ425FIB

CAS#:2425-79-8

Literature: Peng, Wei; Liu, Pei-Yan; Jiang, Ning; Lin, Hong-Hui; Zhang, Guo-Lin; Liu, Yi; Yu, Xiao-Qi Bioorganic Chemistry, 2005 , vol. 33, # 5 p. 374 - 385

Precursor 2
CAS#:110-63-4 1,4-Butanediol CAS#:106-89-8 Epichlorohydrin
DownStream 0

HS Code	2910900090
Summary	2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

A review of the metabolism of 1,4-butanediol diglycidyl ether-crosslinked hyaluronic acid dermal fillers.

Dermatol. Surg. 39(12) , 1758-66, (2013)

Cosmetic procedures are growing ever more common, and the use of soft tissue fillers is increasing. Practicing physicians need to be aware of the biological behavior of these products in tissue to ena...

An attempt to improve diagnostics of contact allergy due to epoxy resin systems. First results of the multicentre study EPOX 2002.

Contact Dermatitis 51(5-6) , 263-72, (2004)

Epoxy resin systems (ERSs) are a frequent cause of occupational allergic contact dermatitis. Sensitization occurs not only to the resins, but also to hardeners and reactive diluents. However, only a f...

Chemical mutagenesis testing in Drosophila. IX. Results of 50 coded compounds tested for the National Toxicology Program.

Environ. Mol. Mutagen. 23(1) , 51-63, (1994)

Fifty chemicals were tested for mutagenic activity in post-meiotic and meiotic germ cells of male Drosophila melanogaster using the sex-linked recessive lethal (SLRL) assay. As in the previous studies...

Oxirane, 2,2'-[1,4-butanediylbis(oxymethylene)]bis-

aralditdy026

ARALDITE RD-2

2,2'-[1,4-Butanediylbis(oxymethylene)]dioxirane

BUDGE

Tetramethylene Glycol Diglycidyl Ether

BUTANEDIOL-DGE

EINECS 219-371-7

2,2'-[Butane-1,4-diylbis(oxymethylene)]dioxirane

UNII:E9μ425FIB

1,4-Bis(2,3-epoxypropyloxy)butane

1,4-butanediol glycidyl ether

Heloxy 67

1,4-diglycidyloxybutane

ChS-RR2

[Tetramethylenebis(oxymethylene)]dioxirane

1,4-bis(2,3-epoxypropoxy)butane

2,2'-[butane-1,4-diylbis(oxymethanediyl)]dioxirane

Butane-1,4-diol diglycidyl ether

MFCD00005146

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: UNII:E9μ425FIB
Price: ￥158.0/5g ￥368.0/25g
Purity: 95.0%
Stocking Period: 2 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,4-Butane diglycidyl ether
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: 1,4-Butanediol diglycidyl ether
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2425-79-8
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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UNII:E9μ425FIB

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Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

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