JAK-IN-26

Modify Date: 2025-09-11 12:50:52

JAK-IN-26 structure	Common Name	JAK-IN-26
	CAS Number	2417134-93-9	Molecular Weight	420.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₄N₆O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of JAK-IN-26

JAK-IN-26 (compound 2) is an orally active JAK inhibitor with good pharmacokinetic characteristics. JAK-IN-26 inhibits IFN-α2B-induced phosphorylation of STAT3 in Jurkat cells (IC50=17.2 nM)[1].

Name	JAK-IN-26

Description	JAK-IN-26 (compound 2) is an orally active JAK inhibitor with good pharmacokinetic characteristics. JAK-IN-26 inhibits IFN-α2B-induced phosphorylation of STAT3 in Jurkat cells (IC50=17.2 nM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK
References	[1]. Zhou M, et al. Pyridine derivatives as TYK2 kinase inhibitors and preparation thereof. China, CN113563309 A 2021-10-29.

Molecular Formula	C₂₂H₂₄N₆O₃
Molecular Weight	420.46
InChIKey	FKCATCQHVCOBCX-UHFFFAOYSA-N
SMILES	CCC(=O)c1cnc(NC(=O)C2CC2)cc1Nc1cccc(-c2ncn(C)n2)c1OC

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