JAK-IN-26

Names

[ Name ]:
JAK-IN-26

Biological Activity

[Description]:

JAK-IN-26 (compound 2) is an orally active JAK inhibitor with good pharmacokinetic characteristics. JAK-IN-26 inhibits IFN-α2B-induced phosphorylation of STAT3 in Jurkat cells (IC50=17.2 nM)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> JAK/STAT Signaling >> JAK

Signaling Pathways >> Epigenetics >> JAK

Signaling Pathways >> Stem Cell/Wnt >> JAK

[References]

[1]. Zhou M, et al. Pyridine derivatives as TYK2 kinase inhibitors and preparation thereof. China, CN113563309 A 2021-10-29.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₄N₆O₃

[ Molecular Weight ]:
420.46

Related Compounds

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