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2417134-93-9

2417134-93-9 structure

2417134-93-9 structure

Name: JAK-IN-26
Chemical Name: JAK-IN-26
CAS Number: 2417134-93-9
Molecular Formula: C₂₂H₂₄N₆O₃
Molecular Weight: 420.46
Catalog: Signaling Pathways Epigenetics JAK
Create Date: 2023-10-16 17:11:09
Modify Date: 2024-04-02 18:59:31
JAK-IN-26 (compound 2) is an orally active JAK inhibitor with good pharmacokinetic characteristics. JAK-IN-26 inhibits IFN-α2B-induced phosphorylation of STAT3 in Jurkat cells (IC50=17.2 nM)[1].

Name	JAK-IN-26

Description	JAK-IN-26 (compound 2) is an orally active JAK inhibitor with good pharmacokinetic characteristics. JAK-IN-26 inhibits IFN-α2B-induced phosphorylation of STAT3 in Jurkat cells (IC50=17.2 nM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK
References	[1]. Zhou M, et al. Pyridine derivatives as TYK2 kinase inhibitors and preparation thereof. China, CN113563309 A 2021-10-29.

Molecular Formula	C₂₂H₂₄N₆O₃
Molecular Weight	420.46