Enpp-1-IN-13

Modify Date: 2025-08-26 21:05:54

Enpp-1-IN-13 structure	Common Name	Enpp-1-IN-13
	CAS Number	2417022-19-4	Molecular Weight	512.03
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₂₂ClN₅OS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Enpp-1-IN-13

Enpp-1-IN-13 (Compound 1a) is an ectonucleotide pyrophosphatase/phosphodiesterase (ENPP) inhibitor with IC50 values of 1.29 μM and 20.2 μM against ENPP1 and ENPP3, respectively. Enpp-1-IN-13 shows anticancer activity[1].

Name	Enpp-1-IN-13

Description	Enpp-1-IN-13 (Compound 1a) is an ectonucleotide pyrophosphatase/phosphodiesterase (ENPP) inhibitor with IC50 values of 1.29 μM and 20.2 μM against ENPP1 and ENPP3, respectively. Enpp-1-IN-13 shows anticancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)
Target	IC50: 1.29 μM (ENPP1), 20.2 μM (ENPP3)[1]
In Vitro	Enpp-1-IN-13 (Compound 1a) (100 μM) shows cytotoxic effect with inhibition of 23.0 ± 2.2%, 35.1 ± 0.8% and 30.4 ± 0.1% against HeLa, MCF-7 and 1321N1 cells, respectively[1].
References	[1]. Ullah S, et al. Synthesis, biological evaluation, and docking studies of new pyrazole-based thiourea and sulfonamide derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase. Bioorg Chem. 2020 Jun;99:103783.

Molecular Formula	C₂₈H₂₂ClN₅OS
Molecular Weight	512.03

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Enpp-1-IN-13

Use of Enpp-1-IN-13

Names

Enpp-1-IN-13 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.