ZB-R-55

Modify Date: 2023-01-17 11:43:40

ZB-R-55 structure	Common Name	ZB-R-55
	CAS Number	2416593-55-8	Molecular Weight	441.491
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₃N₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ZB-R-55

ZB-R-55 is a potent and selective RIPK1 inhibitor with IC50 of 5.7 nM, 10-fold more potent than GSK2982772.ZB-R-55 is a dual-mode RIPK1 inhibitors occupying both the allosteric and the ATP binding pockets.ZB-R-55 exhibits excellent kinase selectivity, good oral pharmacokinetics and good therapeutic effects in the LPS-induced sepsis model.

Name	ZB-R-55

Description	ZB-R-55 is a potent and selective RIPK1 inhibitor with IC50 of 5.7 nM, 10-fold more potent than GSK2982772.ZB-R-55 is a dual-mode RIPK1 inhibitors occupying both the allosteric and the ATP binding pockets.ZB-R-55 exhibits excellent kinase selectivity, good oral pharmacokinetics and good therapeutic effects in the LPS-induced sepsis model.
References	1. Xiangbo Yang, et al. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202114922.

Molecular Formula	C₂₅H₂₃N₅O₃
Molecular Weight	441.491

DC Chemicals Limited
China
Product Name: ZB-R-55
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Get all suppliers and price by the below link:

ZB-R-55 suppliers

ZB-R-55 price

ZB-R-55

Use of ZB-R-55

Names

ZB-R-55 Biological Activity

Chemical & Physical Properties