TRV120055

Modify Date: 2024-07-17 13:09:52

TRV120055 structure	Common Name	TRV120055
	CAS Number	2410957-04-7	Molecular Weight	742.87
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₄H₅₄N₁₂O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TRV120055

TRV120055 is a Gq-biased agonists, exhibits 10-fold larger molecular efficacies at the AT1R-Gq fusion protein compared with the AT1R-βarr2 fusion protein[1].

Name	TRV120055

Description	TRV120055 is a Gq-biased agonists, exhibits 10-fold larger molecular efficacies at the AT1R-Gq fusion protein compared with the AT1R-βarr2 fusion protein[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Rajagopal S, et, al. Quantifying ligand bias at seven-transmembrane receptors. Mol Pharmacol. 2011 Sep;80(3):367-77. [2]. Strachan RT, et, al. Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR). J Biol Chem. 2014 May 16; 289(20): 14211-24.

Description

TRV120055 is a Gq-biased agonists, exhibits 10-fold larger molecular efficacies at the AT1R-Gq fusion protein compared with the AT1R-βarr2 fusion protein[1].

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. Rajagopal S, et, al. Quantifying ligand bias at seven-transmembrane receptors. Mol Pharmacol. 2011 Sep;80(3):367-77.

[2]. Strachan RT, et, al. Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR). J Biol Chem. 2014 May 16; 289(20): 14211-24.

Molecular Formula	C₃₄H₅₄N₁₂O₇
Molecular Weight	742.87

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China
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TRV120055

Use of TRV120055

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TRV120055 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.