Antibacterial agent 98

Modify Date: 2025-08-27 11:32:17

Antibacterial agent 98 Structure
Antibacterial agent 98 structure
 Common Name Antibacterial agent 98
CAS Number 2408695-41-8 Molecular Weight 399.45
Density N/A Boiling Point N/A
Molecular Formula C17H13N5O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antibacterial agent 98


Antibacterial agent 98 (compound g37) is a potent and orally active antibacterial agent. Antibacterial agent 98 inhibits the ATPase activity of Gyrase B and impairs Staphylococcus aureus (S. aureus ) DNA supercoiling. Antibacterial agent 98 shows antibacterial activity and not induce resistance development of MRSA (methicillin-resistant S. aureus)[1].

 Names

Name Antibacterial agent 98

 Antibacterial agent 98 Biological Activity

Description Antibacterial agent 98 (compound g37) is a potent and orally active antibacterial agent. Antibacterial agent 98 inhibits the ATPase activity of Gyrase B and impairs Staphylococcus aureus (S. aureus ) DNA supercoiling. Antibacterial agent 98 shows antibacterial activity and not induce resistance development of MRSA (methicillin-resistant S. aureus)[1].
Related Catalog
In Vitro Antibacterial agent 98 (compound g37) shows antibacterial activity with an NICs of 0.1 μg/mL for S. aureus ATCC29213 and an IC50 of 0.15 µM for GyrB[1]. Antibacterial agent 98 shows cytotoxicity with IC50s of 55.3, 38.8 µM for HepG2, HUVEC cells, respectively[1].
References

[1]. Xue W, et al. N-thiadiazole-4-hydroxy-2-quinolone-3-carboxamides bearing heteroaromatic rings as novel antibacterial agents: Design, synthesis, biological evaluation and target identification. Eur J Med Chem. 2020 Feb 15;188:112022.

 Chemical & Physical Properties

Molecular Formula C17H13N5O3S2
Molecular Weight 399.45
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Chemsrc provides Antibacterial agent 98(CAS#:2408695-41-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Antibacterial agent 98 are included as well.>> amp version: Antibacterial agent 98

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