Anticancer agent 57

Modify Date: 2025-09-21 21:30:49

Anticancer agent 57 Structure
Anticancer agent 57 structure
 Common Name Anticancer agent 57
CAS Number 2408017-71-8 Molecular Weight 378.29
Density N/A Boiling Point N/A
Molecular Formula C20H21Cl2NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Anticancer agent 57


Anticancer agent 57 (compound 14) potently inhibits MDA-MB-231, MDA-MB-468, and MCF-7 cell lines, with IC50s of 6.43 ~ 8.00 μM. Anticancer agent 57 induces cell cycle arrest and significantly promotes apoptosis. Anticancer agent 57 inhibits tumor growth in nude mice xenografted with MADMB-231 cells. Anticancer agent 57 can be used for researching triple negative breast cancer (TNBC)[1].

 Names

Name Anticancer agent 57

 Anticancer agent 57 Biological Activity

Description Anticancer agent 57 (compound 14) potently inhibits MDA-MB-231, MDA-MB-468, and MCF-7 cell lines, with IC50s of 6.43 ~ 8.00 μM. Anticancer agent 57 induces cell cycle arrest and significantly promotes apoptosis. Anticancer agent 57 inhibits tumor growth in nude mice xenografted with MADMB-231 cells. Anticancer agent 57 can be used for researching triple negative breast cancer (TNBC)[1].
Related Catalog
Target

IC50: 8.00 ± 0.07 μM in MDA-MB-231, 7.30 ± 0.04 μM in MDA-MB-468, 6.43 ± 0.18 μM in MCF-7[1]

References

[1]. Elkhalifa D, et al. Design, synthesis, and validation of novel nitrogen-based chalcone analogs against triple negative breast cancer. Eur J Med Chem. 2020;187:111954.

 Chemical & Physical Properties

Molecular Formula C20H21Cl2NO2
Molecular Weight 378.29
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Chemsrc provides Anticancer agent 57(CAS#:2408017-71-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Anticancer agent 57 are included as well.>> amp version: Anticancer agent 57

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