Microcolin H

Modify Date: 2025-11-26 17:10:43

Microcolin H Structure
Microcolin H structure
Common Name Microcolin H
CAS Number 2408008-21-7 Molecular Weight 733.93
Density N/A Boiling Point N/A
Molecular Formula C38H63N5O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Microcolin H


Microcolin H is a marine lipopeptide and phosphatidylinositol transfer protein ligand that targets PITPα/β. Microcolin H increases the conversion of LC3I to LC3II and reduces p62 levels in cancer cells, leading to autophagy cell death (Autophagy). Microcolin H effectively inhibits tumor development and has anti-proliferative activity in nude mouse subcutaneous tumor models[1].

 Names

Name Microcolin H

 Microcolin H Biological Activity

Description Microcolin H is a marine lipopeptide and phosphatidylinositol transfer protein ligand that targets PITPα/β. Microcolin H increases the conversion of LC3I to LC3II and reduces p62 levels in cancer cells, leading to autophagy cell death (Autophagy). Microcolin H effectively inhibits tumor development and has anti-proliferative activity in nude mouse subcutaneous tumor models[1].
Related Catalog
Target

Phosphatidylinositol transfer protein, PITPα/β[1]

References

[1]. Yang H et al. Microcolin H, a novel autophagy inducer, exerts potent antitumour activity by targeting PITPα/β. Signal Transduct Target Ther. 2023 Nov 15;8(1):428.  

 Chemical & Physical Properties

Molecular Formula C38H63N5O9
Molecular Weight 733.93
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