2408008-21-7

2408008-21-7 structure

Name: Microcolin H
Chemical Name: Microcolin H
CAS Number: 2408008-21-7
Molecular Formula: C₃₈H₆₃N₅O₉
Molecular Weight: 733.93
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2024-01-13 09:47:36
Modify Date: 2024-01-13 09:47:36
Microcolin H is a marine lipopeptide and phosphatidylinositol transfer protein ligand that targets PITPα/β. Microcolin H increases the conversion of LC3I to LC3II and reduces p62 levels in cancer cells, leading to autophagy cell death (Autophagy). Microcolin H effectively inhibits tumor development and has anti-proliferative activity in nude mouse subcutaneous tumor models[1].

Name	Microcolin H

Description	Microcolin H is a marine lipopeptide and phosphatidylinositol transfer protein ligand that targets PITPα/β. Microcolin H increases the conversion of LC3I to LC3II and reduces p62 levels in cancer cells, leading to autophagy cell death (Autophagy). Microcolin H effectively inhibits tumor development and has anti-proliferative activity in nude mouse subcutaneous tumor models[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others Signaling Pathways >> Autophagy >> Autophagy
Target	Phosphatidylinositol transfer protein, PITPα/β[1]
References	[1]. Yang H et al. Microcolin H, a novel autophagy inducer, exerts potent antitumour activity by targeting PITPα/β. Signal Transduct Target Ther. 2023 Nov 15;8(1):428.

Molecular Formula	C₃₈H₆₃N₅O₉
Molecular Weight	733.93