BMS-496

Modify Date: 2024-02-01 11:12:02

BMS-496 Structure
BMS-496 structure
Common Name BMS-496
CAS Number 2407854-31-1 Molecular Weight 570.39
Density N/A Boiling Point N/A
Molecular Formula C26H22BrF2N5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BMS-496


BMS-496 is adualDGKα/ζlipid kinase inhibitor, with theIC50of 0.09 (DGKα) and 0.006 μM (DGKζ)[1].

 Names

Name BMS-496

 BMS-496 Biological Activity

Description BMS-496 is adualDGKα/ζlipid kinase inhibitor, with theIC50of 0.09 (DGKα) and 0.006 μM (DGKζ)[1].
Related Catalog
Target

0.09, 0.006 μM (DGKα,DGKζ)[1].

References

[1]. Wichroski M, et al. DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell-mediated antitumor immunity. Sci Transl Med. 2023;15(719):eadh1892.  

 Chemical & Physical Properties

Molecular Formula C26H22BrF2N5O3
Molecular Weight 570.39
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