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2407854-31-1

2407854-31-1 structure

2407854-31-1 structure

Name: BMS-496
Chemical Name: BMS-496
CAS Number: 2407854-31-1
Molecular Formula: C₂₆H₂₂BrF₂N₅O₃
Molecular Weight: 570.39
Catalog: Research Areas Cancer
Create Date: 2024-02-01 11:12:02
Modify Date: 2024-02-01 11:12:02
BMS-496 is adualDGKα/ζlipid kinase inhibitor, with theIC50of 0.09 (DGKα) and 0.006 μM (DGKζ)[1].

Name	BMS-496

Description	BMS-496 is adualDGKα/ζlipid kinase inhibitor, with theIC50of 0.09 (DGKα) and 0.006 μM (DGKζ)[1].
Related Catalog	Research Areas >> Cancer
Target	0.09, 0.006 μM (DGKα,DGKζ)[1].
References	[1]. Wichroski M, et al. DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell-mediated antitumor immunity. Sci Transl Med. 2023;15(719):eadh1892.

Molecular Formula	C₂₆H₂₂BrF₂N₅O₃
Molecular Weight	570.39

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