BMS-496

Names

[ CAS No. ]:
2407854-31-1

[ Name ]:
BMS-496

Biological Activity

[Description]:

BMS-496 is adualDGKα/ζlipid kinase inhibitor, with theIC50of 0.09 (DGKα) and 0.006 μM (DGKζ)[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

0.09, 0.006 μM (DGKα,DGKζ)[1].


[References]

[1]. Wichroski M, et al. DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell-mediated antitumor immunity. Sci Transl Med. 2023;15(719):eadh1892.  

Chemical & Physical Properties

[ Molecular Formula ]:
C26H22BrF2N5O3

[ Molecular Weight ]:
570.39


Related Compounds

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