HPK1-IN-25

Modify Date: 2025-08-26 21:54:53

HPK1-IN-25 structure	Common Name	HPK1-IN-25
	CAS Number	2403600-50-8	Molecular Weight	387.48
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₅N₅O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of HPK1-IN-25

HPK1-IN-25 (example 94) is a hematopoietic progenitor kinase 1 (HPK1) inhibitor with a enzymatic activity IC50 of 129 nM. HPK1-IN-25 has the potential for cancer research[1].

Name	HPK1-IN-25

Description	HPK1-IN-25 (example 94) is a hematopoietic progenitor kinase 1 (HPK1) inhibitor with a enzymatic activity IC50 of 129 nM. HPK1-IN-25 has the potential for cancer research[1].
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> MAP4K Research Areas >> Cancer
Target	HPK1:129 nM (IC50)
References	[1]. Jing Li, et al. Pyrrolo [2, 3-b] pyridines or pyrrolo [2, 3-b] pyrazines as hpk1 inhibitor and the use thereof. WO2019238067A1.

Molecular Formula	C₂₃H₂₅N₅O
Molecular Weight	387.48
InChIKey	BTKNLDIWKHQYBY-UHFFFAOYSA-N
SMILES	COc1ccc(-c2c[nH]c3ncc(-c4cnn(C5CCN(C)CC5)c4)cc23)cc1

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